Job Description

The Chan Zuckerberg Initiative was founded by Priscilla Chan and Mark Zuckerberg in 2015 to help solve some of societys toughest challenges from eradicating disease and improving education to addressing the needs of our local communities. Our mission is to build a more inclusive, just, and healthy future for everyone.

The Team

CZI supports the science and technology that will make it possible to help scientists cure, prevent, or manage all diseases by the end of this century. While this may seem like an audacious goal, in the last 100 years, biomedical science has made tremendous strides in understanding biological systems, advancing human health, and treating disease.

Achieving our mission will only be possible if scientists are able to better understand human biology. To that end, we have identified four grand challenges that will unlock the mysteries of the cell and how cells interact within systems paving the way for new discoveries that will change medicine in the decades that follow:

• Building an AI-based virtual cell model to predict and understand cellular behavior
• Developing state-of-the-art imaging systems to observe living cells in action
• Instrumenting tissues to better understand inflammation, a key driver of many diseases
• Engineering and harnessing the immune system for early detection, prevention, and treatment of disease

CZIs work in science includes grantmaking programs, open-source software development, and close collaboration with the Chan Zuckerberg Biohub Network. The CZ Biohub Network includes the San Francisco, Chicago, and New York Biohubs as well as the Chan Zuckerberg Imaging Institute. CZI also collaborates with institutional partners like the Kempner Institute for the Study of Natural & Artificial Intelligence at Harvard University. Join us in accelerating science.

The Opportunity

The Data Services team manages and processes scientific datasets specifically designed to enable biological modeling. It is responsible for data validation, wrangling, testing, storage, and retrieval. We handle over 89 million unique cells worth of single cell transcriptomic data, over 15 thousand cryoET tomograms that are in imaging datasets as large as 20TB and counting, and will be expanding to support larger scale and additional imaging, sequencing, and literature modalities. Our resources provide access to open source data that is structured and used by tens of thousands of scientists each month to quickly query and form hypotheses on understanding how genetic variants in cells impact disease risk, define drug toxicities, and eventually discover better therapies.

As a software engineer on the Data Engineering team, you will help implement all the data needs for our platforms, CELLxGENE Discover , CryoET , as well as the new platform we are building that has a focus on data for AI and the virtual cell, in order to enable scientists to further interrogate our very large and growing corpus of data without any need to download the data itself or have any computational expertise. You will work on a collaborative, multidisciplinary team to develop solutions for our scientist users to accelerate their workflows and accelerate the pace of scientific discovery.

No prior biology experience is required for this role. You will have the opportunity to pair with Computational Biologists to develop solutions for our users and be able to learn about biology from experts on our team.

What You'll Do

• Develop end-to-end, robust data pipelines that seamlessly integrate data ingestion, preprocessing, feature engineering, model training, and deployment.
• Implement scalable data warehousing solutions to handle massive volumes of single-cell transcriptomics data and imaging data.
• Ensure data security and compliance with industry standards and regulations.
• Implement optimization strategies such as data partitioning, indexing, and compression to enhance query performance and reduce computational costs.
• Create user-friendly APIs to enable researchers and scientists to easily access and explore the curated data.
• Enhance the searchability and findability of scientific datasets.
• Develop scalable, maintainable, and testable software systems and participate in team conversations and efforts on engineering excellence.
• Collaborate with product managers, computational biologists, UX designers, and other software engineers to deliver constant incremental value for scientists without compromising on software quality.
• Have opportunities to learn about scientific data and technologies, though no prior experience is required!

What You'll Bring

• 2+ years of relevant engineering technical experience.
• Understanding of AWS services (S3, RDS, EKS, Batch, etc.)
• Computer Science Engineering degree.
• Strong fundamentals in systems design, data structures, algorithms, and object oriented programming principles.
• Proficiency in Python, awareness of scientific computing libraries, such as NumPy and SciPy
• Strong problem solving and analytical skills.
• Excellent written and verbal communication skills.
• Enthusiasm to ramp up on technologies and learn a new science domain.
• Must be self-driven and comfortable supporting data needs of multiple systems and products.

Compensation

The Redwood City, CA base pay range for this role is $153,000-$230,000. New hires are typically hired into the lower portion of the range, enabling employee growth in the range over time. Actual placement in range is based on job-related skills and experience, as evaluated throughout the interview process.

Benefits for the Whole You

Were thankful to have an incredible team behind our work. To honor their commitment, we offer a wide range of benefits to support the people who make all we do possible.

• CZI provides a generous employer match on employee 401(k) contributions to support planning for the future.
• Annual benefit for employees that can be used most meaningfully for them and their families, such as housing, student loan repayment, childcare, commuter costs, or other life needs.
• CZI Life of Service Gifts are awarded to employees to live the mission and support the causes closest to them.
• Paid time off to volunteer at an organization of your choice.
• Relocation support for employees who need assistance moving to the Bay Area

If youre interested in a role but your previous experience doesnt perfectly align with each qualification in the job description, we still encourage you to apply as you may be the perfect fit for this or another role.

Accepted file types: pdf, doc, docx, txt, rtf

Enter manually

Accepted file types: pdf, doc, docx, txt, rtf

LinkedIn Profile

This role is a hybrid (Open to Flex) role and will require you to be onsite 60% of the working month at our HQ in Redwood City, CA. Will you be able to commit to this? * Select...

Are you currently eligible to work in the United States of America? * Select...

Do you now or in the future require visa sponsorship to continue working in the United States? * Select...

How did you hear about this job? * Select...

If 'Other', please specify how you heard about this job:

Have we met you at one of our events? If so, which one(s)? *

CZI-Sponsored Meetups

CZI-Sponsored Conferences

University Events / Career Fairs

None

Would you like to be invited to our recruiting events and receive information about what is happening at CZI? Youll have the option to opt out at any time. * Select...

In the last 12 months, have you applied to any organization(s) within the Chan Zuckerberg Science ecosystem? * Select...

We have many exciting career opportunities available, and as part of our collaborative approach, we work with our hiring teams across our wider network to identify talent for our openings. Please opt-in or opt-out here if you would like us to share your profile for other opportunities. * Select...

Reasonable Accommodation and Data Privacy Notice. * Select...

Reasonable Accommodation Notice
CZI provides (and state and federal law requires) reasonable accommodations to qualified individuals with disabilities. Please tell us if you require a reasonable accommodation to apply for a job or to perform your job (reach out to your recruiter or accommodations@chanzuckerberg.com ). Examples of reasonable accommodation include making a change to the application process or work procedures, providing documents in an alternate format, using a sign language interpreter, or using specialized equipment.

For reporting purposes, we ask candidates to respond to the below self-identification survey. Completion of the form is entirely voluntary. Whatever your decision, it will not be considered in the hiring process or thereafter. Any information that you do provide will be recorded and maintained in a confidential file.

As set forth in Chan Zuckerberg Initiatives Equal Employment Opportunity policy, we do not discriminate on the basis of any protected group status under any applicable law.

If you believe you belong to any of the categories of protected veterans listed below, please indicate by making the appropriate selection. Classification of protected categories is as follows:

A "disabled veteran" is one of the following: a veteran of the U.S. military, ground, naval or air service who is entitled to compensation (or who but for the receipt of military retired pay would be entitled to compensation) under laws administered by the Secretary of Veterans Affairs; or a person who was discharged or released from active duty because of a service-connected disability.

A "recently separated veteran" means any veteran during the three-year period beginning on the date of such veteran's discharge or release from active duty in the U.S. military, ground, naval, or air service.

An "active duty wartime or campaign badge veteran" means a veteran who served on active duty in the U.S. military, ground, naval or air service during a war, or in a campaign or expedition for which a campaign badge has been authorized under the laws administered by the Department of Defense.

An "Armed forces service medal veteran" means a veteran who, while serving on active duty in the U.S. military, ground, naval or air service, participated in a United States military operation for which an Armed Forces service medal was awarded pursuant to Executive Order 12985.

Job Tags

Similar Jobs